Upload a VCF file, annotate with gnomAD, ClinVar, AlphaMissense, Pangolin, and HPO scores, then explore filtered variants by gene, disease, or panel — all in one interface.
Built for clinical and research teams who need answers fast — not another tool that gets in the way.
gnomAD, ClinVar, AlphaMissense, Pangolin, BayesDel, HPO, and AdenineAI disease associations annotated in under 2 minutes.
Chain bcftools screens with quick filters — rare, pathogenic, de novo, recessive, comp-het, splice, frameshift — in one click.
Drill into any gene, disease, or curated panel. Chip-level counts show exactly how many variants match each gene under your current filters.
Merge proband, mother and father VCFs automatically. Inheritance flags — de novo, recessive, compound het — computed on the fly.
Save any variant with rich-text notes and custom tags. Build a shortlist as you work, shareable with your whole team.
Auth0-backed authentication, Pundit-enforced case access control. Share cases with collaborators at read or write permission.
Upload a VCF file and have prioritised, annotated variants on your screen in under 2 minutes.